Mr A, a 59-year-old combat veteran of the Vietnam War, was diagnosed with PTSD on Axis I according to DSM-IV-TR. 1 It has been postulated that posttraumatic stress disorder (PTSD)-related nightmares arise from fragmentation of rapid eye movement sleep. To the Editor: There have been numerous studies on the use of prazosin for nightmares, but data on doxazosin are very limited. Cognitive-behavioral therapy for sleep disturbances in treating posttraumatic stress disorder symptoms: A meta-analysis of randomized controlled trials.Doxazosin for the Treatment of Nightmares: Does It Really Work? A Case Report Comparative meta-analysis of prazosin and imagery rehearsal therapy for nightmare frequency, sleep quality, and posttraumatic stress. Trial of prazosin for post-traumatic stress disorder in military veterans. Comparative efficacy and acceptability of pharmaceutical management for adults with post-traumatic stress disorder: A systematic review and meta-analysis. Aetiology and treatment of nightmare disorder: State of the art and future perspectives. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Studies also show that CBT combined with IRT can improve treatment outcomes leading to better sleep quality in people with PTSD. One 2015 review of a number of studies concluded that sleep-specific CBT was an effective treatment for PTSD symptoms, such as sleep disturbances. Studies show that CBT can be an effective treatment for helping manage PTSD symptoms, including sleep disturbances. ![]() Cognitive behavioral therapy (CBT)ĬBT is a type of talk therapy that focuses on the way people think and interpret events in their life.ĭuring a CBT session, a therapist will work with a patient to explore and develop methods to deal with certain challenges and behaviors. It revealed that both prazosin and IRT showed comparable and moderate effects on PTSD nightmares and other symptoms. ![]() Studies show that IRT is a powerful strategy for treating PTSD nightmares.Ī 2015 meta-analysis looked at the short-term effects of prazosin compared to IRT on nightmares, sleep quality, and PTSD symptoms. IRT also helps a person learn how to monitor their nightmares in order to understand how effective the therapy is. They can write down these endings and rehearse them mentally. The individual then works closely with their therapist to create their own nonfrightening endings for the nightmares they experience. This can help a person manage their nightmares. IRT is a form of cognitive behavioral therapy (CBT).ĭuring IRT, a therapist will provide the individual with background information about sleep and nightmares. Imagery rehearsal therapy (IRT) is a possible treatment for PTSD nightmares. There are several other nonmedical treatments that a person may wish to consider to help them manage their nightmares. ![]() These affect less than 1% of people that take the drug and include: There are also some very rare side effects. Other less common side effects, which affect between 1–4% of people, include: This is a temporary loss of consciousness that may be related to a lack of blood flow to the brain. ![]() People may also develop orthostatic hypotension, which is a form of hypotension that occurs when a person stands up after sitting or lying down.Ī person taking prazosin may also develop syncope, which is another name for fainting. First-dose hypotension can be serious, so doctors recommend that a person takes their initial dose at night. More serious but less common side effects include hypotension, or low blood pressure. The most common of these affect between 5–10% of people, and include: Prazosin has several potential side effects.
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